21 Short FcRn-binding peptides enable salvage and transcytosis of scFv antibody fragments
Kelly VW, and Sirk SJ. ACS Chemical Biology 17 (2), 404-413 (2022)
20 Living Therapeutics: The Next Frontier of Precision Medicine
Kelly VW, Liang BK, and Sirk SJ. ACS Synthetic Biology 9 (12), 3184-3201 (2020)
19 A metabolic pathway for activation of dietary glucosinolates by a human gut symbiont
Liou CS*, Sirk SJ*, Diaz CAC*, Klein AP, Fischer CR, Higginbottom SK, Erez A, Donia MS, Sonnenburg JL, and Sattely ES *Equal contribution. Cell 180, 717-28 (2020)
18 Directed evolution of targeted recombinases for genome engineering
Sirk SJ, Methods in Molecular Biology 1867, 89-102 (2018)
17 Genome-editing technologies: principles and applications
Gaj T, Sirk SJ, Shui S, and Liu J. Cold Spring Harbor Perspectives in Biology 12, a023754 (2016)
16 Protein delivery using Cys2–His2 zinc-finger domains
Gaj T, Liu J, Anderson KE, Sirk SJ, and Barbas CF. ACS Chemical Biology 9, 1662-7 (2014)
15 Enhancing the specificity of recombinase-mediated genome engineering through dimer interface redesign
Gaj T, Sirk SJ, Tingle R, Mercer AC, Wallen MA, and Barbas CF. Journal of the American Chemical Society 136, 5047-56 (2014)
14 Expanding the zinc-finger recombinase repertoire: directed evolution and mutational analysis of serine recombinase specificity determinants
Sirk SJ, Gaj T, Jonsson A, Mercer AC, and Barbas CF. Nucleic Acids Research 42, 4755-66 (2014)
13 Cell-penetrating peptide-mediated delivery of TALEN proteins via bioconjugation for genome engineering
Liu J, Gaj T, Patterson JT, Sirk SJ, and Barbas CF. PLOS ONE 9, e85755 (2014)
12 Expanding the scope of site‐specific recombinases for genetic and metabolic engineering
Gaj T, Sirk SJ, and Barbas CF. Biotechnology & Bioengineering 111, 1-15 (2014)
11 Regulation of endogenous human gene expression by ligand-inducible TALE transcription factors
Mercer AC, Gaj T, Sirk SJ, Lamb BM, and Barbas CF. ACS Synthetic Biology 3, 723-30 (2014)
10 Antibody conjugation approach enhances breadth and potency of neutralization of anti-HIV-1 antibodies and CD4-IgG
Gavrilyuk J, Ban H, Uehara H, Sirk SJ, Saye-Francisco K, Cuevas A, Zablowsky E, Oza A, Seaman MS, Burton DR, and Barbas CF. Journal of Virology 87, 4985-93 (2013)
9 A comprehensive approach to zinc-finger recombinase customization enables genomic targeting in human cells
Gaj T, Mercer AC, Sirk SJ, Smith HL, and Barbas CF. Nucleic Acids Research 41, 3937-46 (2013)
8 Targeted gene knockout by direct delivery of zinc-finger nuclease proteins
Gaj T, Guo J, Kato Y, Sirk SJ, and Barbas CF. Nature Methods 9, 805-7 (2012)
7 ImmunoPET using engineered antibody fragments: fluorine-18 labeled diabodies for same-day imaging
Olafsen T, Sirk SJ, Olma S, Shen CKF, and Wu AM. Tumor Biology 33, 669-77 (2012)
6 Microfluidic-based 18F-Labeling of biomolecules for immuno–positron emission tomography
Liu K, Lepin EJ, Wang MW, Guo F, Lin WY, Chen YC, Sirk SJ, Olma S, Phelps ME, Zhao XZ, Tseng HR, van Dam RM, Wu AM, and Shen CKF. Molecular Imaging 10, 168-76 (2011)
5 ImmunoPET imaging of B-cell lymphoma using 124I-anti-CD20 scFv dimers (diabodies)
Olafsen T, Sirk SJ, Betting DJ, Kenanova VE, Bauer KB, Ladno W, Raubitschek AA, Timmerman JM, and Wu AM. Protein Engineering, Design & Selection 23, 243-249 (2010)
4 Cys-diabody quantum dot conjugates (immunoQdots) for cancer marker detection
Barat B, Sirk SJ, McCabe KE, Li J, Lepin EJ, Remenyi R, Koh AL, Olafsen T, Gambhir SS, Weiss S, and Wu AM. Bioconjugate Chemistry 20, 1474-81 (2009)
3 Site-specific, thiol-mediated conjugation of fluorescent probes to cysteine-modified diabodies targeting CD20 or HER2
Sirk SJ, Olafsen T, Barat B, Bauer KB, and Wu AM. Bioconjugate Chemistry 19, 2527-34 (2008)
2 Measurement of amphotericin B concentration by resonant Raman spectroscopy – a novel technique that may be useful for non-invasive monitoring
La Via WV, Lambert JL, Pelletier MJ, Morookian JM, Sirk SJ, Mickiene D, Walsh TJ, and Borchert MS. Medical Mycology 44, 169-74 (2006)
1 Measurement of aqueous glucose in a model anterior chamber using Raman spectroscopy
Lambert JL, Morookian JM, Sirk SJ, and Borchert MS. Journal of Raman Spectroscopy 33, 524-29 (2002)